PICO

4 results

Efficacy and safety of switching to bictegravir, emtricitabine, and tenofovir alafenamide in virologically suppressed Asian adults living with HIV: A pooled analysis from three international phase III randomized trials.

Avihingsanon A, Chetchotisakd P, Kiertiburanakul S, Ratanasuwan W, Siripassorn K, Supparatpinyo K, Martin H, Wang H, Wong T, Wang HY - HIV medicine, March 14, 2023 3 citations

Asian people living with HIV

I/C

switching to bictegravir, emtricitabine, and tenofovir alafenamide (B/F/TAF), staying on baseline regimens

maintained 100% virological suppression at week 48 with no treatment-emergent drug resistance and safety profiles comparable to those seen in people who stayed on baseline regimens

Tenofovir disoproxil fumarate for prevention of mother-to-child transmission of hepatitis B virus: A systematic review and meta-analysis of randomised control trials.

Zeleke ED, Assefa DG, Joseph M, Bekele D, Tesfahunei HA, Getachew E, Manyazewal T - Reviews in medical virology, January 24, 2021 2 citations

651 participants

I/C

tenofovir disoproxil fumarate (TDF), standard of care, placebo or other HBV therapies

HBV MTCT rate and maternal HBV DNA level

Adverse effects of daily oral pre-exposure prophylaxis in men who have sex with men and transgender women: a systematic review and meta-analysis.

Pereira M, Castro CT, Magno L, Oliveira TA, Gomes FS, Neves FMF, Nascimento PRDSD, Dourado I - Cadernos de saude publica, December 13, 2023 0 citations

men who have sex with men (MSM), transgender women (TGW)

I/C

daily oral pre-exposure prophylaxis (PrEP) using tenofovir disoproxil fumarate, no PrEP

adverse effects

Pharmacokinetic Outcomes of the Interactions of Antiretroviral Agents with Food and Supplements: A Systematic Review and Meta-Analysis.

Siritientong T, Thet D, Methaneethorn J, Leelakanok N - Nutrients, March 13, 2022 4 citations

people living with the human immunodeficiency virus (PLWH)

I/C

concurrent administration of antiretroviral drugs (ARV) with food or nutritional products, food-drug coadministration

pharmacokinetic outcomes of the interaction between supplements and ARV

Papers