PICO

3 results

Surgical treatment of stage IV colorectal cancer with synchronous liver metastases: A systematic review and network meta-analysis.

Ghiasloo M, Pavlenko D, Verhaeghe M, Van Langenhove Z, Uyttebroek O, Berardi G, Troisi RI, Ceelen W - European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, March 18, 2020 30 citations

patients with colorectal cancer (CRC) and synchronous liver metastases (SCRLM)

I/C

bowel-first approach (BFA), simultaneous resection (SIM), liver-first approach (LFA), BFA vs. LFA, SIM vs. LFA

postoperative complications, 30- and 90-day mortality, chemotherapy use, treatment completion rate, 3- and 5-year recurrence-free survival, 3- and 5-year overall survival (OS)

Calcium Phosphate Carrying Simvastatin Enhances Bone Regeneration: A Systematic Review.

Cruz R, Pesce G, Calasans-Maia J, Moraschini V, Calasans-Maia MD, Granjeiro JM - Brazilian dental journal, June 20, 2020 7 citations

animal models

I/C

calcium phosphate carried simvastatin, cloth or calcium phosphate alone

bone formation and regeneration

Comparative Lipid-Lowering/Increasing Efficacy of 7 Statins in Patients with Dyslipidemia, Cardiovascular Diseases, or Diabetes Mellitus: Systematic Review and Network Meta-Analyses of 50 Randomized Controlled Trials.

Zhang X, Xing L, Jia X, Pang X, Xiang Q, Zhao X, Ma L, Liu Z, Hu K, Wang Z, Cui Y - Cardiovascular therapeutics, May 16, 2020 29 citations

51956 participants

I/C

7 different statins (simvastatin, fluvastatin, atorvastatin, rosuvastatin, lovastatin, pravastatin, and pitavastatin), comparing the lipid-lowering efficacy of no less than two of the included statins (or statin vs. placebo)

LDL-C lowering

Papers