Papers

64 results
Effect of Immune-Related Adverse Events and Pneumonitis on Prognosis in Advanced Non-Small Cell Lung Cancer: A Comprehensive Systematic Review and Meta-analysis.
Li Y, Zhang Y, Jia X, Jiang P, Mao Z, Liang T, Du Y, Zhang J, Zhang G, Niu G, Guo H - Clinical lung cancer, June 30, 2021 11 citations
P
12,600 participants
I/C
checkpoint inhibitor pneumonitis (CIP), endocrine and skin irAEs, severe-grade irAEs, low-grade irAEs, multiple irAEs, 1 irAE
O
overall survival (OS), objective response rate (ORR)
Immune Checkpoint Inhibitors and Immune-Related Adverse Events in Patients With Advanced Melanoma: A Systematic Review and Network Meta-analysis.
Chang CY, Park H, Malone DC, Wang CY, Wilson DL, Yeh YM, Van Boemmel-Wegmann S, Lo-Ciganic WH - JAMA network open, March 27, 2020 73 citations
P
advanced melanoma patients
I/C
immune checkpoint inhibitors (ICIs), ipilimumab, nivolumab, pembrolizumab, chemotherapy drugs (eg, dacarbazine, carboplatin, and paclitaxel)
O
cumulative incidence of any irAEs (regardless of severity), severe irAEs (grades 3-5)
P
TNBC, metastatic TNBC, early TNBC
I/C
ICI, immune checkpoint inhibitors, different ICI agents
O
progression-free survival (PFS), overall survival (OS), pathologic complete response rate (pCR), grade ≥ 3 treatment-related adverse events (trAEs), immune-related adverse events (irAEs), grade ≥ 3 irAEs
Roux-en-Y with or without jejunal J-pouch reconstruction after total gastrectomy for gastric cancer: systematic review and meta-analysis of long-term functional outcomes.
Realis Luc M, Bonomi AM, Carbone F, Ascari F, de Pascale S, Fumagalli Romario U - Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, March 06, 2024 1 citations
P
patients undergoing total gastrectomy for gastric cancer
I/C
J-pouch (JP) reconstruction, standard Roux-en-Y (RY) esophagojejunostomy
O
dumping syndrome, heartburn symptoms
P
cancer patients
I/C
immune checkpoint inhibitors (ICIs), no immune checkpoint inhibitors
O
immune-related adverse events (irAEs)
Adverse events of neoadjuvant combination immunotherapy for resectable cancer patients: a systematic review and meta-analysis.
Feng Y, Guo K, Jin H, Jiang J, Wang M, Lin S - Frontiers in immunology, January 22, 2024 0 citations
P
patients with cancer
I/C
neoadjuvant combination immunotherapy, standard of care
O
incidence of immune-related adverse events (irAEs)
Adverse events associated with immune checkpoint inhibitors in patients with breast cancer: A systematic review and meta-analysis.
Balibegloo M, Nejadghaderi SA, Sadeghalvad M, Soleymanitabar A, Salehi Nezamabadi S, Saghazadeh A, Rezaei N - International immunopharmacology, June 25, 2021 14 citations
P
adults with breast cancer
I/C
immune checkpoint inhibitors (ICIs), other conventional therapies
O
any-grade and grade 3-5 adverse events (AEs) and immune-related AEs (irAEs)
Meta-Analysis of Optimal Revascularization Strategy for Patients With ST-Segment Elevation Myocardial Infarction and Multi-Vessel Coronary Artery Disease.
Shah R, Nayyar M, Le FK, Labroo A, Davis DA, Brilakis ES, Kandzari DE - The American journal of cardiology, June 17, 2020 2 citations
P
patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease
I/C
complete revascularization (CR), infarct-related artery-only revascularization (IRA-OR)
O
cardiovascular (CV) mortality, myocardial infarction (MI), recurrent revascularization
P
cancer patients with preexisting autoimmune diseases (AID)
I/C
immune checkpoint inhibitors (ICI), no ICI treatment
O
incidence of autoimmune flare, irAE, response rate, and ICI discontinuation
Efficacy and safety of neoadjuvant PD-1 inhibitors or PD-L1 inhibitors for muscle invasive bladder cancer: a systematic review and meta-analysis.
Huang S, Huang Y, Li C, Liang Y, Huang M, Luo R, Liang W - Frontiers in immunology, January 24, 2024 1 citations
P
muscle-invasive bladder carcinoma
I/C
neoadjuvant PD-(L)1 inhibitors, PD-(L)1 inhibitors alone, PD-(L)1 inhibitors plus other ICI, PD-(L)1 inhibitors plus chemotherapy
O
pCR, pPR, Grade≥ 3 irAEs rate, OS, RFS
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