PICO

12 results

Cytoreductive surgery for advanced epithelial ovarian cancer in the poly(ADP-ribose) polymerase inhibitors era-Is it time for a new paradigm shift? A systematic review and meta-analysis.

Peters ITA, Marchetti C, De Palma A, Giannarelli D, Carcagnì A, Scambia G, Fagotti A - European journal of cancer (Oxford, England : 1990), May 02, 2023 6 citations

patients with newly diagnosed advanced high-grade serous and endometrioid epithelial ovarian cancer (EOC)

I/C

poly(ADP-ribose) polymerase inhibitors (PARPi), placebo

progression-free survival (PFS)

PARP Inhibitors in Metastatic Prostate Cancer: A Comprehensive Systematic Review and Meta-analysis of Existing Evidence.

Ditonno F, Bianchi A, Malandra S, Porcaro AB, Fantinel E, Negrelli R, Ferro M, Milella M, Brunelli M, Autorino R, Cerruto MA, Veccia A, Antonelli A - Clinical genitourinary cancer, January 29, 2024 1 citations

metastatic castration-resistant prostate cancer (mCRPC) patients

I/C

Poly (ADP-ribose) polymerase inhibitors (PARPi), approved (Olaparib, Rucaparib) and investigational (Talazoparib, Niraparib, Veliparib)

PSA decline ≥ 50% from baseline, objective response rate, progression-free survival (PFS), radiological PFS, overall survival (OS), conversion of circulating tumor cell count, time to PSA progression

Poly (ADP-ribose) polymerase inhibitors in solid tumours: Systematic review and meta-analysis.

Schettini F, Giudici F, Bernocchi O, Sirico M, Corona SP, Giuliano M, Locci M, Paris I, Scambia G, De Placido S, Rescigno P, Prat A, Curigliano G, Generali D - European journal of cancer (Oxford, England : 1990), April 17, 2021 41 citations

8,839 patients

I/C

PARPis, Control arm

Progression-free survival (PFS), Overall response rate (ORR), Overall survival (OS)

Clinical guidelines for ovarian cancer: the Korean Society of Gynecologic Oncology guidelines.

Lee B, Chang SJ, Kwon BS, Son JH, Lim MC, Kim YH, Lee SW, Choi CH, Eoh KJ, Lee JY, Suh DH, Kim YB - Journal of gynecologic oncology, January 05, 2024 0 citations

Epithelial Ovarian Cancer (EOC) patients

I/C

Poly-ADP ribose polymerase inhibitors, Intraperitoneal plus intravenous chemotherapy, Secondary cytoreductive surgery, Platinum-sensitive recurrent ovarian cancer

Efficacy and safety

Impact of saturated compared with unsaturated dietary fat on insulin sensitivity, pancreatic β-cell function and glucose tolerance: a systematic review and meta-analysis of randomized, controlled trials.

Lytrivi M, Gomes Da Silveira Cauduro C, Kibanda J, Kristanto P, Paesmans M, Cnop M - The American journal of clinical nutrition, July 28, 2023 3 citations

1586

I/C

replacing dietary saturated fatty acids (SFA) with mono- or poly-unsaturated fatty acids (MUFA and PUFA), SFA compared with MUFA

insulin sensitivity, β-cell function, and glucose tolerance

Survival and modelled cancer antigen-125 ELIMination rate constant K score in ovarian cancer patients in first-line before poly(ADP-ribose) polymerase inhibitor era: A Gynaecologic Cancer Intergroup meta-analysis.

Corbaux P, You B, Glasspool RM, Yanaihara N, Tinker AV, Lindemann K, Ray-Coquard IL, Mirza MR, Subtil F, Colomban O, Péron J, Karamouza E, McNeish I, Kelly C, Kagimura T, Welch S, Lewsley LA, Paoletti X, Cook A - European journal of cancer (Oxford, England : 1990), August 06, 2023 4 citations

patients with advanced ovarian cancer

I/C

CA-125 ELIMination rate constant K (KELIM), surgery outcome

overall survival (OS) and progression-free survival (PFS)

Sonolysis of per- and poly fluoroalkyl substances (PFAS): A meta-analysis.

Sidnell T, Wood RJ, Hurst J, Lee J, Bussemaker MJ - Ultrasonics sonochemistry, June 11, 2022 39 citations

I/C

sonolysis

degradation of PFAS

Magnitude of benefit of the addition of poly ADP-ribose polymerase (PARP) inhibitors to therapy for malignant tumor: A meta-analysis.

Gu L, Du N, Jin Q, Li S, Xie L, Mo J, Shen Z, Mao D, Ji J, Khadaroo PA, Chen B - Critical reviews in oncology/hematology, February 06, 2020 14 citations

I/C

The prevalence of stunting among children and adolescents living in the Middle East and North Africa region (MENA): A systematic review and meta-analysis.

Joulaei H, Keshani P, Ashourpour M, Bemani P, Amiri S, Rahimi J, Aliakbarpour M, Salehi-Abargouei A - Journal of global health, January 11, 2022 7 citations

children 2 to 18 years of age

I/C

systematic review of English-language articles published between January 1, 2009 and December 31, 2019, subgroups based on age, residential area, and HDI

prevalence of stunting as an indicator of chronic malnutrition in the MENA region

PARP-inhibitors for BRCA1/2-related advanced HER2-negative breast cancer: A meta-analysis and GRADE recommendations by the Italian Association of Medical Oncology.

Miglietta F, Cinquini M, Dieci MV, Cortesi L, Criscitiello C, Montemurro F, Del Mastro L, Zambelli A, Biganzoli L, Levaggi A, Delle Piane C, Marchiò C, Calabrese M, Fortunato L, Franco P, Meduri B, Fittipaldo VA, Gori S - Breast (Edinburgh, Scotland), November 16, 2022 5 citations

BRCA1/2 germline mutations

I/C

olaparib, talazoparib, single-agent chemotherapy

PFS, ORR, QoL

Papers