Tissue Infiltrating Immune Cells as Prognostic Biomarkers in Endometrial Cancer: A Meta-Analysis.
endometrial cancer patients
tumour-infiltrating immune cells
high CD8
overall survival (OS), progression-free survival (PFS), disease-specific survival (DSS), and disease-free survival (DFS)
Abstract
The association between tumour-infiltrating immune cells and the prognosis of endometrial cancer (EC) is controversial due to the smaller sample sizes and limited statistical power of the extant studies. We carried out a meta-analysis of the relationship between tumour-infiltrating immune cells and EC survival outcomes. A literature search in multiple databases was carried out up to December 2019. Pooled hazard ratio (HRs) and 95% confidence intervals (CIs) were calculated by the Seventeen studies were included in the analysis. The pooled HR of OS, PFS, DSS, and DFS indicated that a high CD8 This is the first meta-analysis of the relationship between tumour-infiltrating immune cells and the prognosis of EC. High CD8