Accuracy of the estimation of
healthy population, dialysis population
isotopic dilution, anthropometric equations (e.g. Watson formula), bioimpedance analysis
between-method population means
typically within 1-1.5 L of each other, larger bias seen when applying anthropometric equations to different racial groups, 95% LOA for all comparisons were consistently wide, typically ranging ±12-18% of the TBW
Abstract
Current guidelines for the prescription of peritoneal dialysis dose rely on a single cut-off 'minimal' value of A literature search was undertaken of studies comparing TBW estimation using two or three of the following methods: isotopic dilution (gold standard), anthropometric equations (e.g. Watson formula) and bioimpedance analysis. Studies of healthy and dialysis populations of all ages were included. Mean differences and 95% limits of agreement (LOA) were extracted and pooled. In 44 studies (31 including dialysis subjects), the between-method population means were typically within 1-1.5 L of each other, although larger bias was seen when applying anthropometric equations to different racial groups. However, the 95% LOA for all comparisons were consistently wide, typically ranging ±12-18% of the TBW. For a typical individual whose TBW is 35 L with a measured There are limitations to the accuracy of estimation of