Normative values for esophageal functional lumen imaging probe measurements: A meta-analysis.
healthy adults
Endoflip™, measurements of esophageal motility
no intervention
esophagogastric junction distensibility index (EGJ-DI)
Abstract
The functional lumen imaging probe (Endoflip™) is increasingly used for evaluation of patients with esophageal symptoms. To improve the interpretation of Endoflip™ in clinical practice, normative values with appropriate cut-off values are required. Original clinical studies describing Endoflip™ use for measurements of esophageal motility in healthy adults were considered. Meta-analysis was performed based on published values. A total of 17 articles were included in the systematic review, 15 of which were included in the meta-analysis, representing 154 unique subjects. At 40 ml distention, the 5th-95th and 10th-90th percentiles for esophagogastric junction distensibility index (EGJ-DI) were 1.96-10.95 mm Given these observations, we recommend using a cut-off of 2 mm