Adult weight gain and the risk of cardiovascular disease: a systematic review and dose-response meta-analysis of prospective cohort studies.
Published
March 24, 2020
Journal
European journal of clinical nutrition
PICOID
b40667f8
DOI
Citations
32
Keywords
Copyright
Patients/Population/Participants
1,093,337
Intervention
: weight gain during adulthood
Comparison
random-effect models
Outcome
risk of cardiovascular disease (CVD)
Abstract
P
I
C
O
We aimed to examine the association of weight gain during adulthood with the risk of cardiovascular disease (CVD) in the general population. We performed a systematic search of PubMed and Scopus, from inception to June 2019. Prospective cohort studies investigating the association of weight gain during adulthood with the risk of CVD were included. The relative risks (RRs) were calculated by using random-effect models. Twenty-three prospective cohort studies with 1,093,337 participants were included. The RRs for a 5-kg increment in body weight were 1.11 (95% CI: 1.04, 1.19; I