Parenteral Vitamin C in Patients with Severe Infection: A Systematic Review.
Published
September 01, 2022
Journal
NEJM evidence
PICOID
81559ce9
DOI
Citations
23
Keywords
Copyright
Patients/Population/Participants
patients with severe infection
Intervention
parenteral vitamin C
Comparison
no clear evidence
Outcome
survival benefit
Abstract
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Parenteral Vitamin C in Patients with Severe InfectionIn this systematic review and meta-analysis of mortality outcomes in trials of vitamin C for severe infection, including the recently reported LOVIT trial, Agarwal et al. find no clear evidence of survival benefit among published blinded trials at low risk-of-bias.