Published
July 06, 2020
Journal
European journal of radiology
PICOID
7b69f9f9
DOI
Citations
17
Keywords
(68)Ga-PSMA, Meta-analysis, PET/MRI, Prostate cancer
Copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Patients/Population/Participants

patients with primary prostate cancer

Intervention

PET/MRI

Comparison

BCR

Outcome

detection rate

Abstract

P
I
C
O

Our meta-analysis aimed to evaluate the diagnostic performance of We searched for relevant articles in PubMed, EMBASE, the Cochrane Library and Web of Science until September 12, 2019. Studies regarding the diagnostic performance of A total of 13 studies with 707 patients were included in the analysis, and the pooled sensitivity and specificity of PET/MRI in detecting primary PCa were 0.83 (95 % CI, 0.73-0.90) and 0.81 (95 % CI, 0.61-0.93), respectively. In the pooled analysis of BCR, the pooled detection rate was 76 % (95 % CI, 72 %-79 %). For four levels of PSA (0-0.2 ng/mL, 0.2-1 ng/mL, 1-2 ng/mL and more than 2 ng/mL), the pooled detection rates were 38 %, 67 %, 74 %, and 95 %, respectively. There was no distinct publication bias, but there was significant study heterogeneity.

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