PD-L1 rs2890658 Polymorphism Increases Risk for Non-Small-Cell Lung Cancer in Northern China Population Based on Experimental Data and Meta-Analysis.
Published
August 23, 2022
Journal
Contrast media & molecular imaging
PICOID
62a66dcb
DOI
Citations
2
Keywords
Copyright
Copyright © 2022 Guigang Wang et al.
Patients/Population/Participants
individuals with CC genotype, individuals with C allele
Intervention
PD-L1 rs2890658 polymorphism
Comparison
individuals with AA genotype, individuals with A allele
Outcome
increased risk of developing NSCLC
Abstract
P
I
C
O
To dig the PD-L1 rs2890658 polymorphism with susceptibility of non-small-cell lung cancer (NSCLC) in northern China. It is more likely that individuals who have CC genotype and C allele are 2.15 and 1.41 times to develop NSCLC compared with individuals with AA genotype and A allele, respectively. Meta-analysis showed that the individuals who have C allele and CA genotype increased the risk of suffering from NSCLC. PD-L1 rs2890658 polymorphism increased NSCLC risk in northern China population and it might predict the occurrence of NSCLC.