Psychological treatment of perinatal depression: a meta-analysis.

Published
June 13, 2023
Journal
Psychological medicine
PICOID
5dfa6400
DOI
Citations
28
Keywords
Antenatal depression, cognitive behavior therapy, interpersonal psychotherapy, meta-analysis, perinatal depression, postpartum depression, randomized controlled trials
Copyright
Patients/Population/Participants

perinatal women with depression

Intervention

psychological interventions

Comparison

control group

Outcome

effective treatment of perinatal depression, improved social support, anxiety, functional impairment, parental stress, and marital stress

Abstract

P
I
C
O

Depression during pregnancy and after the birth of a child is highly prevalent and an important public health problem. Psychological interventions are the first-line treatment and, although a considerable number of randomized trials have been conducted, no recent comprehensive meta-analysis has evaluated treatment effects. We used an existing database of randomized controlled trials of psychotherapies for adult depression and included studies aimed at perinatal depression. Random effects models were used in all analyses. We examined the effects of the interventions in the short and long term, and also examined secondary outcomes. Forty-three studies with 49 comparisons and 6270 participants between an intervention and control group were included. The overall effect size was Psychological interventions are probably effective in the treatment of perinatal depression, with effects that last at least up to 6-12 months and probably also have effects on social support, anxiety, functional impairment, parental stress, and marital stress.

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