Impact of prior bariatric surgery on risk and severity of COVID-19 infection: A meta-analysis of observational studies.
patients
prior bariatric surgery (BS)
coronavirus disease 2019 (COVID-19)
mortality, hospital/intensive care unit (ICU) admission, mechanical ventilation, acute kidney injury (AKI), infection rate
Abstract
The association of prior bariatric surgery (BS) with infection rate and prognosis of coronavirus disease 2019 (COVID-19) remains unclear. We conducted a meta-analysis of observational studies to address this issue. We searched databases including MEDLINE, Embase, and CENTRAL from inception to May, 2022. The primary outcome was risk of mortality, while secondary outcomes included risk of hospital/intensive care unit (ICU) admission, mechanical ventilation, acute kidney injury (AKI), and infection rate. Eleven studies involving 151,475 patients were analyzed. Meta-analysis showed lower risks of mortality [odd ratio (OR)= 0.42, 95% CI: 0.27-0.65, p < 0.001, I Our results showed a correlation between prior BS and less severe COVID-19, which warrants further investigations to verify.