Effect of calorie restriction diet on levels of C reactive protein (CRP) in obesity: A systematic review and meta-analysis of randomized controlled trials.
Published
February 27, 2022
Journal
Diabetes & metabolic syndrome
PICOID
3995dced
DOI
Citations
4
Keywords
CRP, Obesity, Restricted calorie diet
Copyright
Copyright © 2022. Published by Elsevier Ltd.
Patients/Population/Participants
obese patients
Intervention
calorie-restricted diet
Comparison
non-diet interventions
Outcome
reduced C-reactive protein (CRP)
Abstract
P
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Chronic inflammation in obese patients can be managed through a calorie-restricted diet, characterized by reduced C - reactive protein (CRP). This study aims to assess the role of such diet on CRP. Literature searches were performed using search engines. Randomized controlled trials were included. Calorie-restricted diets in combination with non-diet interventions were excluded. Calorie restriction decreased CRP in obese patients with a mean difference of -0.22 (95% CI -0.40 to -0.04, p 0.006). Calorie-restricted diet reduces CRP. Diet administration >12 weeks had a beneficial effect.