Incidence and relevant factors for seizures after spontaneous intracerebral hemorrhage: A systematic review and meta-analysis.

Published
July 20, 2022
Journal
Seizure
PICOID
302e40d4
DOI
Citations
1
Keywords
ICH, Meta-analysis, Relevant factors, Seizures
Copyright
Copyright © 2022. Published by Elsevier Ltd.
Patients/Population/Participants

32,162

Intervention

alcohol consumption, cortical involvement, lobular location, hematoma volume, hematoma evacuation, treatment with ASM, age, GCS score at presentation, hypertension

Comparison

no seizures

Outcome

seizures

Abstract

P
I
C
O

To identify the incidence and relevant factors for seizures after spontaneous intracerebral hemorrhage (sICH) by performing a systematic review and meta-analysis. We systematically searched PubMed, EMBASE, and Cochrane Library from inception to 14 August 2021 for studies investigating relevant factors associated with seizures after sICH. A meta-analysis of all included studies was performed by using Stata version 12.0 software. In total, 22 studies with 32,162 participants were included. The meta-analysis showed a 9.5% incidence of seizures after sICH. We identified 6 factors that increased the risk of seizures after sICH, including alcohol consumption(RR (95% CI) =1.26 (1.07, 1.48) , I The incidence of seizures after ICH is 9.5%. Alcohol consumption, cortical involvement, lobar location, hematoma volume, hematoma evacuation, treatment with ASM, age, GCS score at presentation, and hypertension are closely tied to the occurrence of seizures after sICH.

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